We are distributors of Calibre Scientific's micromanipulation instruments line
Micromanipulation
Micromanipulation is the main technique used to perform cell manipulation experiments and medical procedures related to in vitro fertilization.
In research, physical manipulation exposes cells to less trauma compared to conventional laboratory methods such as chemical transfection or electroporation, thus contributing to the quality of results.
Calibre Scientific represents the ideal partner for micromanipulation and microinjection in life science, providing a complete line of products suitable for a wide range of applications.
Microinjection into suspension cells
Production of genetically modified animals using pronuclear and cytoplasmic injection (e.g. CRISPR)
Applications in animal reproductive medicine (e.g. mouse ICSI)
Serial injection into fish embryos (e.g. Zebrafish, Medaka)
Injection into C. elegans, other worms, insects, etc.
Manipulation of suspension cells
Stem cell transfer
Nuclear transfer
Transplantation of cells into small organisms or 3D cell culture
Selection and isolation of individual cells (e.g. biopsies)
Other application examples
Semi-automatic microinjection into adherent cells
Positioning and selection of microparticles
Microdissection of chromosomes, etc.
Automatic dispensing of cell suspensions or solutions
Precision, Processing Speed and Ease of Use, these are the main characteristics of Calibre instruments, which will make your work as simple as possible.
Electronic micromanipulators, electronic and manual microinjectors, specific consumables and accessories.
The electronics that “characterize this line make the” entire system reliable, easy to use and semi-automatic for some applications. The “exceptional immediacy and smoothness of movements in all directions make Calibre Scientific micromanipulators ergonomic platforms ideal for use in different experimental areas”
TRANSFERMAN 4m/4r or INJECTMAN 4
For capillary movement of holding and microinjection capillary. Easy to use, it combines ergonomics and an innovative operating concept, ideal for manipulating suspension cells such as oocytes and blastocysts. The ability to have customized, application-specific profiles simplifies the work process and allows you to choose from 4 predefined application masks (e.g., for cell transfer, DNA injection, etc.). Main features:
maximum stability ensuring vibration-free work
Joystick for precise movement control on 4 axes: X, Y, Z and X/Z (axial)
Programmable Z-axis limit to prevent capillary breakage
CELLTRAM Air/Oil
Manual pneumatic or hydraulic microinjectors, designed with particular attention to optimal ergonomics, for operating comfort and high precision. The CellTram Air is a pneumatic microinjector for a wide range of microtransfer techniques. It’s ideal for holding suspended cells or embryos or for dispensing smaller volumes of liquid. The CellTram Oil is ideal for sophisticated applications requiring high resolution and sensitivity (e.g., embryonic biopsies or injection into plant cells). All models offer simplicity and reliable performance suitable for all applications and meeting even the most demanding requirements.
FEMTOJET
Instrument suitable for injecting small to intermediate volumes (up to 1 µL) with a wide range of features, simple operation and electronics with connection to the TransferMan or InjectMan, simplifying control of the injection process. The instrument allows standardization of the injection process by setting pressure and volume values, resulting in reproducible work